The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Jul. 30, 2021
Applicants:
Shenzhen Catalys Technology Co., Ltd, Guangdong, CN;
Shenzhen Innovation Center of Small Molecule Drug Discovery Co., Ltd., Guangdong, CN;
Inventors:
Assignees:
SHENZHEN CATALYS TECHNOLOGY CO., LTD, Shenzhen, CN;
Shenzhen Innovation Center of Small Molecule Drug Discovery Co., Ltd., Shenzhen, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 209/26 (2006.01); C07C 213/02 (2006.01); C07C 269/06 (2006.01);
U.S. Cl.
CPC ...
C07C 209/26 (2013.01); C07C 213/02 (2013.01); C07C 269/06 (2013.01); C07C 2602/10 (2017.05); C07C 2602/12 (2017.05);
Abstract
The present invention relates to a preparation method of chiral primary amine. The chiral primary amine is prepared through a one-pot method that under the action of a ruthenium-chiral diphosphine catalyst, a simple ketone and an ammonium salt RCOONHhave reductive amination by adding hydrogen and then are heated and hydrolyzed by adding acid. The present invention has the advantages of good substrate universality, high reaction efficiency and the like