The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2024

Filed:

Feb. 16, 2023
Applicant:

Sericulture and Agri-food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, CN;

Inventors:

Tiantian Zhao, Guangzhou, CN;

Yehui Zhang, Guangzhou, CN;

Yousheng Zhang, Guangzhou, CN;

Wenjuan Jiao, Guangzhou, CN;

Weifeng Liu, Guangzhou, CN;

Shuai Chen, Guangzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61P 1/14 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61P 1/14 (2018.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); C12P 21/06 (2013.01);
Abstract

The present disclosure belongs to the technical field of health food, and in particular, relates to the use of PAYCS in the regulation of intestinal flora, metabolites, and brain neurotransmitters. PAYCS remedies scopolamine-induced memory impairment in mice through target oxidation, inflammatory stress and regulation of the intestinal microorganism-metabolite-brain neurotransmitter axis through PAYCS. PAYCS improves the memory pathway through the intestinal microorganism-metabolite-neurotransmitter axis. PAYCS can significantly reduce serum MDA and LDH levels and significantly increase liver SOD content. PAYCS-H inhibits the increase of liver TNF-α and IL-1β, while PAYCS-L can only reduce the content of TNF-α in the liver. Thus, PAYCS-L changes the ratio of/Firmicutes and increases the relative abundance of plants such as Cactaceae and Prevotellaceae, improving the neurotransmitters associated with the metabolism of tryptophan in the brain.


Find Patent Forward Citations

Zhao, Tiantian. (2024). Use of paycs in regulation of intestinal flora, metabolites, and brain neurotransmitters (U.S. Patent No. 12128084). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12128084

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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