The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2024
Filed:
Oct. 23, 2020
Integrated Dna Technologies, Inc., Coralville, IA (US);
Jessica Woodley, North Liberty, IA (US);
Bernice Thommandru, Iowa City, IA (US);
Joseph Dobosy, Coralville, IA (US);
Mark Behlke, Coralville, IA (US);
Adam Clore, Iowa City, IA (US);
Garrett Rettig, Coralville, IA (US);
Beimeng Sun, North Liberty, IA (US);
INTEGRATED DNA TECHNOLOGIES, INC., Coralville, IA (US);
Abstract
Described herein are compositions and methods for improving homology directed repair (HDR) efficiency and reducing homology-independent integration following introduction of double strand breaks with engineered nucleases. Additionally, modifications to double stranded DNA donors to improve the donor potency and efficiency of homology directed repair following introduction of double stranded breaks with programmable nucleases.