The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 22, 2024

Filed:

Mar. 20, 2023
Applicant:

Temasek Life Sciences Laboratory Limited, Singapore, SG;

Inventors:

Lianghui Ji, Singapore, SG;

Si Te Ngoh, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/14 (2006.01); C12P 17/06 (2006.01); C12R 1/645 (2006.01);
U.S. Cl.
CPC ...
C12N 1/14 (2013.01); C12N 1/145 (2021.05); C12P 17/06 (2013.01); C12N 2500/22 (2013.01); C12N 2500/24 (2013.01); C12N 2500/42 (2013.01); C12R 2001/645 (2021.05);
Abstract

A culture for the fermentative production oflactone comprising anspecies in a culture medium, wherein thespecies expresses no functional Aureobasidin A synthase gene mRNA when cultured, the culture medium including KHPO, NaHPO, (NH)SO, MgSO·7HO and CaCl·2HO; at least two trace elements selected from the group consisting of Fe, Cu, Znand MoO; urea; and a carbon source selected from the group consisting of glucose, mannose, xylose and mixtures thereof, wherein the culture medium has a pH from 5.5 to 6.5.


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