The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 15, 2024

Filed:

Feb. 02, 2021
Applicant:

L.e.a.f. Holdings Group Llc, Gulph Mills, PA (US);

Inventors:

Clet Niyikiza, Gulph Mills, PA (US);

Victor Moyo, Ringoes, NJ (US);

Zhenghong Xu, Arlington, MA (US);

Kaniz Khalifa, Billericsa, MA (US);

Assignee:

L.E.A.F. HOLDINGS GROUP LLC, Gulph Mills, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 31/337 (2006.01); A61K 31/4745 (2006.01); A61K 31/555 (2006.01); A61K 31/7068 (2006.01); A61K 31/716 (2006.01); A61K 33/243 (2019.01); A61K 45/06 (2006.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 31/337 (2013.01); A61K 31/4745 (2013.01); A61K 31/555 (2013.01); A61K 31/7068 (2013.01); A61K 33/243 (2019.01); A61K 45/06 (2013.01); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6913 (2017.08); A61P 31/18 (2018.01); A61P 35/00 (2018.01); C07K 16/28 (2013.01); C07K 16/30 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01);
Abstract

This disclosure relates to a targeted PEGylated liposomal gemcitabine (PLG) composition comprising a PEGylated liposome encapsulating one or more agents comprising gemcitabine and a targeting moiety; pharmaceutical composition and methods comprising PLG or producing PLG; and manufacturing equipment for performing the methods.


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