The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2024

Filed:

Aug. 29, 2019
Applicant:

Genomatica, Inc., San Diego, CA (US);

Inventors:

Stephen Thomas Payne, South San Francisco, CA (US);

Scott Allen Frykman, South San Francisco, CA (US);

Bernardo Moura Torres Da Costa, South San Francisco, CA (US);

Isolde Callihan, South San Francisco, CA (US);

Sankaranarayanan Venkiteswaran, South San Francisco, CA (US);

Leland Ken Wong, South San Francisco, CA (US);

Assignee:

Genomatica, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/245 (2006.01); C12N 1/22 (2006.01); C12N 9/02 (2006.01); C12N 9/06 (2006.01); C12N 9/10 (2006.01); C12N 9/18 (2006.01); C12P 7/6436 (2022.01);
U.S. Cl.
CPC ...
C07K 14/245 (2013.01); C12N 1/22 (2013.01); C12N 9/0008 (2013.01); C12N 9/0014 (2013.01); C12N 9/0077 (2013.01); C12N 9/1029 (2013.01); C12N 9/1096 (2013.01); C12N 9/18 (2013.01); C12P 7/6436 (2013.01); C12Y 102/99006 (2013.01); C12Y 104/99003 (2013.01); C12Y 114/15003 (2013.01); C12Y 203/01075 (2013.01); C12Y 206/01001 (2013.01); C12Y 301/01067 (2013.01);
Abstract

The disclosure relates to mutant gene(s) that confer upon microorganisms that express them an improved capacity to utilize xylose and improved capacity to co-utilize glucose and xylose thereby resulting in improved growth of the microorganism. Further encompassed are methods of producing fatty acids and fatty acid derivatives from cellulosic biomass, xylose, and/or a glucose/xylose mix by employing the host cells expressing the engineered XylR variants and compositions of biologically produced fatty acids and fatty acid derivatives.


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