The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Mar. 05, 2021
Altratech Limited, Limerick, IE;
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Rockville, MD (US);
Brian O'Farrell, Watergrasshill, IE;
Claire O'Connell, Stamullen, IE;
Kaylyn Oshaben, Summerhill, PA (US);
Daniel Appella, Bethesda, MD (US);
Altratech Limited, Limerick, IE;
The United States of America, as represented by the Secretary, Department of Health and Human Services, Rockville, MD (US);
Abstract
A method of target enrichment or depletion from a sample with an analyte is described. A probe has one of a left-handed PNA pair and a targeting moiety, in which the left-handed PNA pair are a complementary pair of PNAs that are chiral and have a cyclic backbone modification that induces a left-handed helical structure. A capture surface has the other of the left-handed PNA pair; and the left-handed PNA pair bind to hybridize the probe to the capture surface, which may be a magnetic bead.