The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 2024
Filed:
Apr. 30, 2021
Arcturus Therapeutics, Inc., San Diego, CA (US);
Carlos G. Perez-Garcia, San Diego, CA (US);
Kiyoshi Tachikawa, San Diego, CA (US);
Daiki Matsuda, San Diego, CA (US);
Padmanabh Chivukula, San Diego, CA (US);
Priya Prakash Karmali, San Diego, CA (US);
Yanjie Bao, San Diego, CA (US);
Jerel Boyd Lee Vega, San Diego, CA (US);
Rajesh Mukthavaram, San Diego, CA (US);
Amit Sagi, San Diego, CA (US);
Arcturus Therapeutics, Inc., San Diego, CA (US);
Abstract
Nucleotides encoding a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein are provided herein. Also describe are mRNA constructs that can be used to express CFTR protein in vitro or in vivo. The mRNA constructs can be formulated in a lipid formulation and administered via inhalation to treat cystic fibrosis.