The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 06, 2024

Filed:

Aug. 26, 2020
Applicant:

10x Genomics, Inc., Pleasanton, CA (US);

Inventors:

Vijay Kumar Sreenivasa Gopalan, Santa Clara, CA (US);

Paul Ryvkin, San Jose, CA (US);

Zachary Bent, Pleasanton, CA (US);

Jessica Michele Terry, Pleasanton, CA (US);

David Jaffe, Pleasanton, CA (US);

Patrick Marks, San Francisco, CA (US);

Tarjei Sigurd Mikkelsen, Dublin, CA (US);

Assignee:

10X GENOMICS, INC., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6844 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12N 15/1096 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6844 (2013.01);
Abstract

The present disclosure provides methods and systems for producing full-length sequencing information of transcriptomes from single cells or from the bulk. Random ligation and circularization of barcoded or non-barcoded complementary deoxyribonucleic molecules can be used to provide a circular template for amplification and subsequent sequencing.


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