The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Sep. 14, 2022
Applicant:
China Pharmaceutical University, Nanjing, CN;
Inventors:
Qidong You, Nanjing, CN;
Xiaoke Guo, Nanjing, CN;
Dongdong Li, Nanjing, CN;
Weilin Chen, Nanjing, CN;
Zhihui Wang, Nanjing, CN;
Assignee:
HUYABIO International, LLC, San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 249/06 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); C07D 249/06 (2013.01); C07D 401/12 (2013.01); C07D 403/10 (2013.01);
Abstract
The present disclosure relates to the field of medicinal chemistry, in particular to a phenyl triazole MLL1-WDR5 protein-protein interaction inhibitor (I) and a preparation method thereof, and pharmacodynamics experiments prove that the compound of the present disclosure has relatively strong MLL1-WDR5 protein-protein interaction inhibition activity.