The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2024
Filed:
Apr. 20, 2023
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Yung-Hsiang Kao, San Mateo, CA (US);
Michael W. Laird, San Ramon, CA (US);
Melody Trexler Schmidt, Danville, CA (US);
Rita L. Wong, Redwood City, CA (US);
Daniel P. Hewitt, Sunnyvale, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 1/14 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2887 (2013.01); A61K 39/39591 (2013.01); C07K 1/14 (2013.01); C07K 2317/24 (2013.01);
Abstract
The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.