The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2024
Filed:
Mar. 18, 2019
Applicant:
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Inventors:
Juan R. Del Valle, Tampa, FL (US);
Chih-Chi Andrew Hu, Tampa, FL (US);
Assignee:
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC., Tampa, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A01K 67/0276 (2024.01); A61K 31/37 (2006.01); A61K 31/395 (2006.01); A61K 31/436 (2006.01); A61K 31/519 (2006.01); A61K 31/52 (2006.01); A61K 31/55 (2006.01); A61K 33/243 (2019.01); A61K 45/06 (2006.01); C07D 311/16 (2006.01); C07D 311/18 (2006.01); C07D 491/052 (2006.01);
U.S. Cl.
CPC ...
C07D 311/16 (2013.01); A01K 67/0276 (2013.01); A61K 31/37 (2013.01); A61K 31/395 (2013.01); A61K 31/436 (2013.01); A61K 31/519 (2013.01); A61K 31/52 (2013.01); A61K 31/55 (2013.01); A61K 33/243 (2019.01); A61K 45/06 (2013.01); C07D 311/18 (2013.01); C07D 491/052 (2013.01); A01K 2217/075 (2013.01); A01K 2217/077 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01);
Abstract
Disclosed are XBP-1/IRE-1 inhibitors having formula disclosed herein. Methods of making and using these inhibitors for the treatment of cancer, in particular B cell cancers, are also disclosed. Also disclosed is a genetic XBP-1-knockout cancer mouse model.
Del Valle, Juan. (2024). Inhibitors of the ire-1/xbp-1 pathway and methods of using thereof (U.S. Patent No. 11945789). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11945789
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile