The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2023
Filed:
Dec. 04, 2017
Applicant:
Janssen Pharmaceuticals, Inc., Titusville, NJ (US);
Inventors:
Kurt Iver Kamrud, San Diego, CA (US);
Maung Nyan Win, San Diego, CA (US);
Nathaniel Stephen Wang, San Diego, CA (US);
Jason L. DeHart, San Diego, CA (US);
Assignee:
Janssen Pharmaceuticals, Inc., Titusville, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/63 (2013.01); A61K 48/005 (2013.01); C12N 15/113 (2013.01); C12N 15/86 (2013.01); C07K 2319/50 (2013.01); C12N 2015/8518 (2013.01); C12N 2310/531 (2013.01); C12N 2770/00042 (2013.01); C12N 2770/36062 (2013.01); C12N 2770/36111 (2013.01); C12N 2770/36143 (2013.01); C12N 2830/30 (2013.01); C12N 2840/105 (2013.01);
Abstract
The present disclosure generally relates to nucleic acid molecules for use in regulating gene expression. Disclosed herein include nucleic acid molecules containing one or more structural elements of the viral capsid enhancer operably linked to a coding sequence of a gene of interest. In some embodiments, the viral capsid enhancer comprises a Downstream Loop (DLP) from a viral capsid protein, or a variant of the DLP.