The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Sep. 27, 2021
Applicant:

Nanjing Tech University, Nanjing, CN;

Inventors:

Xiaoqiang Chen, Nanjing, CN;

Tingwen Wei, Nanjing, CN;

Jing Wang, Nanjing, CN;

Yanyan Wang, Nanjing, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 227/04 (2006.01); C07D 209/20 (2006.01); C07D 235/22 (2006.01); C07D 403/06 (2006.01);
U.S. Cl.
CPC ...
C07C 227/04 (2013.01); C07D 209/20 (2013.01); C07D 235/22 (2013.01); C07D 403/06 (2013.01);
Abstract

The present disclosure provides a method for photocleavage of an amide bond, the method has mild reaction conditions and can realize the cleavage of amide bonds by using light. The method comprises the following steps: subjecting 2,4-dinitrofluorobenzene to a reaction with an amino group of a substance represented by structural formula I with an α-amino acid at the end to produce a compound 1 represented by structural formula II; then under light irradiation, subjecting the compound 1 to a cleavage reaction of amide bond; Wherein, R1 is the side chain group of α-amino acid; R2 is: aryl, aliphatic hydrocarbon, —CH(R)—COOH or polypeptide.


Find Patent Forward Citations

Chen, Xiaoqiang. (2023). Method for photocleavage of amide bonds (U.S. Patent No. 11845708). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11845708

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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