The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
May. 12, 2020
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Robert H. Brown, Jr., Needham, MA (US);
Janice A. Dominov, North Reading, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12Q 1/6883 (2018.01); C07K 16/18 (2006.01); C12N 15/86 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); C07K 16/18 (2013.01); C12N 15/86 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6872 (2013.01); C07K 2317/34 (2013.01); C12N 2310/11 (2013.01); C12N 2320/33 (2013.01); C12N 2320/53 (2013.01); C12N 2750/14143 (2013.01); C12Q 2600/156 (2013.01); G01N 2333/705 (2013.01); G01N 2800/2878 (2013.01);
Abstract
Aspects of the disclosure relate to methods of altering RNA splicing in a subject. In some embodiments, methods are provided for correcting splicing in a cell that contains a DYSF gene having a mutation that results in defective splicing.