The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2023
Filed:
Aug. 25, 2017
Sanofi, Paris, FR;
Ercole Rao, Frankfurt am Main, DE;
Christian Beil, Frankfurt am Main, DE;
Christian Lange, Frankfurt am Main, DE;
Katja Kroll, Frankfurt am Main, DE;
Wulf-Dirk Leuschner, Frankfurt am Main, DE;
Ingo Focken, Frankfurt am Main, DE;
Thomas Langer, Frankfurt am Main, DE;
Nadja Spindler, Frankfurt am Main, DE;
SANOFI, Paris, FR;
Abstract
Provided herein are multispecific antibodies, e.g. bispecific antibodies, which are modified such that the desired chain pairing takes place and/or can be selected for. Specifically, this is achieved by using different dimerization domains for light chain pairing. Also disclosed herein are nucleic acids encoding for these antibodies, expression vectors comprising these nucleic acids, cells expressing them, and further to pharmaceutical compositions comprising the antibodies, as well as methods of isolating the antibodies.