The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2023

Filed:

Jul. 12, 2018
Applicants:

International Aids Vaccine Initiative, New York, NY (US);

The Scripps Research Institute, La Jolla, CA (US);

The Texas A&m University System, College Station, TX (US);

Inventors:

Devin Sok, New York, NY (US);

Dennis R. Burton, La Jolla, CA (US);

Vaughn V. Smider, La Jolla, CA (US);

Ian Wilson, La Jolla, CA (US);

Michael Criscitiello, College Station, TX (US);

Waithaka Mwangi, College Station, TX (US);

Assignees:

International AIDS Vaccine Initiative, New York, NY (US);

The Scripps Research Institute, La Jolla, CA (US);

THE TEXAS A&M UNIVERSITY SYSTEM, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/10 (2006.01); C07K 14/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1063 (2013.01); C07K 14/162 (2013.01); A61K 38/00 (2013.01); C07K 2317/10 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2319/02 (2013.01); C07K 2319/31 (2013.01);
Abstract

The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab')2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.


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