The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2023
Filed:
Aug. 04, 2021
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
Markus Kalkum, Azusa, CA (US);
Yoko Fujita-Yamaguchi, Pasadena, CA (US);
Karine Bagramyan, North Hollywood, CA (US);
Teresa B. Hong, El Monte, CA (US);
Sarah Shuck, Orange, CA (US);
Assignee:
CITY OF HOPE, Duarte, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 14/36 (2006.01); G01N 33/58 (2006.01); A61K 51/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/36 (2013.01); A61K 51/08 (2013.01); G01N 33/57419 (2013.01); G01N 33/57438 (2013.01); G01N 33/57492 (2013.01); G01N 33/582 (2013.01); C07K 2319/60 (2013.01);
Abstract
Disclosed herein are a recombinantS27S5 hemagglutinin (SHA), and homologues thereof, and a fusion protein of a fluorescent protein (such as GFP and mCherry1) and SHA or a homologue thereof, which specifically bind to carbohydrates, including oligomeric sugars that terminate in L-rhamnose or D-galactose. The SHA, SHA homologues, and fusion proteins can be used to detect a variety of microorganisms or cancer or tumor antigens.