The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Sep. 13, 2022
Precision Biosciences, Inc., Durham, NC (US);
Gary Owens, Durham, NC (US);
Janel Lape, Wake Forest, NC (US);
James Jefferson Smith, Morrisville, NC (US);
John Morris, Raleigh, NC (US);
Caitlin Turner, Durham, NC (US);
Whitney Lewis, Oxford, NC (US);
Derek Jantz, Durham, NC (US);
Precision BioSciences, Inc., Durham, NC (US);
Abstract
The present disclosure encompasses engineered meganucleases that bind and cleave recognition sequences within a dystrophin gene. The present disclosure also encompasses methods of using such engineered meganucleases to make genetically modified cells. Further, the disclosure encompasses pharmaceutical compositions comprising engineered meganuclease proteins, or polynucleotides encoding engineered meganucleases of the disclosure, and the use of such compositions for the modification of a dystrophin gene in a subject, or for treatment of Duchenne Muscular Dystrophy.