The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

Aug. 17, 2018
Applicants:

The Johns Hopkins University, Baltimore, MD (US);

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Honggang Cui, Lutherville, MD (US);

Yi Li, Baltimore, MD (US);

Lye Lin Lock, Maynard, MA (US);

XuanKuo Xu, Boxborough, MA (US);

Zhengjian Li, Sudbury, MA (US);

Assignees:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); C07K 7/08 (2006.01); C07K 14/31 (2006.01); B01J 20/24 (2006.01); B01D 15/38 (2006.01); B01J 20/28 (2006.01); B01J 20/34 (2006.01); C07K 16/06 (2006.01);
U.S. Cl.
CPC ...
B01J 20/24 (2013.01); B01D 15/3809 (2013.01); B01J 20/28023 (2013.01); B01J 20/3425 (2013.01); B01J 20/3475 (2013.01); C07K 1/22 (2013.01); C07K 7/08 (2013.01); C07K 14/31 (2013.01); C07K 16/065 (2013.01);
Abstract

The present invention provide novel immunofiber compositions for protein or peptide purification and simple and cost-efficient methods and systems using these compositions. In some embodiments, the immunofibers comprise a customized Z-33 peptide derived fromProtein A which is used to construct immuno-amphiphile molecules that assemble into immunofibers in aqueous solution with bioactive epitopes on the surface and have peptide or protein binding ability.


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