The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2023
Filed:
Apr. 11, 2020
Applicant:
International Business Machines Corporation, Armonk, NY (US);
Inventors:
Pablo Meyer Rojas, Brooklyn, NY (US);
Gustavo Alejandro Stolovitzky, Riverdale, NY (US);
Assignee:
International Business Machines Corporation, Armonk, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/10 (2006.01); C12Q 1/6869 (2018.01); C40B 20/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/1096 (2013.01); C12Q 1/6869 (2013.01); C40B 20/04 (2013.01);
Abstract
Techniques for positional delivery and position encoding by oligonucleotides of biological cells for single cell RNA sequencing are provided. In one aspect, a method of positional delivery and encoding of cells in a biological sample includes: encoding the cells in the biological sample for single cell sequencing by delivering molecular probes inside the cells that encode a position of the cells in the biological sample. A system for positional delivery and encoding of cells in a biological sample is also provided.