The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2023
Filed:
Mar. 18, 2020
Applicant:
Fraunhofer-gesellschaft Zur Förderung Der Angewandten Forschung E.v., Munich, DE;
Inventors:
Andreas Von Knethen, Nidderau, DE;
Michael Parnham, Bad Soden/Ts., DE;
Lisa Katharina Sha, Hattgenstein, DE;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 47/68 (2017.01); A61P 37/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1774 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61K 47/6811 (2017.08); A61K 47/6835 (2017.08); A61P 9/00 (2018.01); A61P 37/00 (2018.01); C07K 2319/30 (2013.01);
Abstract
The present invention pertains to a fusion polypeptide for use in treating and/or preventing organ failure in a subject suffering from sepsis, said fusion polypeptide comprises at least (i) a first portion being a Fc portion of an immunoglobulin and (ii) a second portion comprising the extracellular portion of the human B7-H1 polypeptide or a variant thereof. Moreover, also encompassed by the invention is a polynucleotide encoding said fusion polypeptide for use in treating and/or preventing organ failure in a subject suffering from sepsis.