The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2023

Filed:

Mar. 23, 2018
Applicant:

Biomedical Analysis Center, Academy of Military Medical Sciences, Beijing, CN;

Inventors:

Xuemin Zhang, Beijing, CN;

Xinhua He, Beijing, CN;

Tao Zhou, Beijing, CN;

Zhenggang Liu, Beijing, CN;

Tao Li, Beijing, CN;

Shengming Wu, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 43/23 (2006.01); C07C 41/40 (2006.01); C07C 41/09 (2006.01);
U.S. Cl.
CPC ...
C07C 43/23 (2013.01); C07C 41/09 (2013.01); C07C 41/40 (2013.01); C07B 2200/13 (2013.01); C07C 2601/16 (2017.05);
Abstract

The present invention relates to a stable crystal form, i.e. form A, of 2-tert-butyl-4-methoxyphenol, and to a new preparation method for the 2-tert-butyl-4-methoxyphenol; and the use of the 2-tert-butyl-4-methoxyphenol and the stable crystal form thereof, i.e. form A, in preparing antitumor drugs or immunomodulator drugs. The stable crystal form, i.e. form A, as expressed by a powder X-ray diffraction pattern in an angle of 2θ, using Cu-Kα radiation, has at least 3 absorption peaks selected from the following positions: 6.27±0.10, 6.94±0.10, 12.27±0.10, 13.36±0.10, 14.01±0.10, 14.79±0.10, 15.31±0.10, 17.05±0.10, 18.30±0.10, 19.00±0.10, 20.47±0.10, 20.98±0.10, 22.37±0.10, 23.68±0.10, 24.55±0.10, 25.37±0.10, 30.83±0.10, 33.12±0.10, 40.50±0.10, 42.81±0.10.


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