The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Jun. 29, 2022
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Adam Castoreno, Framingham, MA (US);
Jason Gilbert, Hingham, MA (US);
Charalambos Kaittanis, Cambridge, MA (US);
James D. McIninch, Burlington, MA (US);
Stuart Milstein, Arlington, MA (US);
Mark K. Schlegel, Boston, MA (US);
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The disclosure relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting a SOD1 gene, as well as methods of inhibiting expression of a SOD1 gene and methods of treating subjects having a SOD1-associated neurodegenerative disease or disorder, e.g., Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease (AD), Parkinson's disease (PD), and Down's syndrome (DS), using such dsRNAi agents and compositions.