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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11635363 B1

PDFFull Text
Date of Patent:
Apr. 25, 2023

Filed:

Oct. 07, 2016

Flare (flow cytometry attenuated reporter expression) technology for rapid bulk sorting

Applicant:

Genzyme Corporation, Cambridge, MA (US);

Inventors:

Victor R. Cairns, Bridgewater, NJ (US);

Jose Ignacio Sancho Chavida, Bridgewater, NJ (US);

Christine DeMaria, Bridgewater, NJ (US);

Assignee:

GENZYME CORPORATION, Cambridge, ME (US);

Attorneys:

Lathrop GPM LLP

James H. Velema, Esq.

Primary Examiner:

Robert J Yamasaki

Int. Cl.
CPC ...
G01N 15/14 (2006.01); C12N 15/10 (2006.01); C07K 16/00 (2006.01); G01N 33/50 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
G01N 15/14 (2013.01); C07K 16/00 (2013.01); C12N 15/1086 (2013.01); C12N 15/85 (2013.01); G01N 33/5044 (2013.01); C07K 2317/10 (2013.01); C12N 2510/02 (2013.01); G01N 2015/149 (2013.01); G01N 2333/70592 (2013.01);
Abstract

Provided herein are methods and compositions for batch production of producer cells using fluorescence activated cell sorting (FACS). In some aspects, the disclosure provides a drug-selection-free method for batch production of producer cells using FACS. Such batch production methods and compositions can be further utilized to generate clonal populations of producer cells, e.g., for large-scale manufacturing of a polypeptide of interest.

Find Patent Forward Citations

Cairns, Victor. (2023). Flare (flow cytometry attenuated reporter expression) technology for rapid bulk sorting (U.S. Patent No. 11635363). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11635363

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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