The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 2023

Filed:

Dec. 10, 2020
Applicants:

Jeol Ltd., Tokyo, JP;

Riken, Wako, JP;

Inventor:

Yusuke Nishiyama, Tokyo, JP;

Assignees:

JEOL Ltd., Tokyo, JP;

RIKEN, Wako, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 24/08 (2006.01); G01R 33/30 (2006.01); G01R 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 24/08 (2013.01); G01R 33/30 (2013.01); G01R 33/50 (2013.01);
Abstract

Nuclear spins of particular atoms (14N) which distinctively exist in a crystal of an active pharmaceutical ingredient is manipulated, so that an initial magnetization (modulated magnetization) is caused in nearby hydrogen atoms which exist near the particular atoms in the crystal. The initial magnetization of the nearby hydrogen atoms is spread to peripheral hydrogen atoms which exist at a periphery of the nearby hydrogen atoms in the crystal. A magnetization which is spread in the crystal is directly or indirectly observed.


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