The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 21, 2023
Filed:
Aug. 19, 2020
Industry Foundation of Chonnam National University, Gwangju, KR;
Korea Institute of Ocean Science & Technology, Busan, KR;
Geun Joong Kim, Gwangju, KR;
Hye Ji Choi, Jeollanam-do, KR;
Dae Eun Cheong, Gwangju, KR;
Su Kyoung Yoo, Gwangju, KR;
Dong Hyun Lee, Gwangju, KR;
Jae Hong Park, Gwangju, KR;
Jung Hyun Lee, Busan, KR;
Hyung Soon Yim, Seoul, KR;
Young Jun An, Gyeonggi-do, KR;
Kyeong Won Lee, Busan, KR;
INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, Gwangju, KR;
KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY, Busan, KR;
Abstract
A recombinant vector according to an embodiment of the present invention may produce fibroblast growth factor 19 (FGF19) having enhanced solubility. The synonymous codon substitution variant fibroblast growth factor 19 (scvhFGF19) and chaperone ΔssDsbC may be simultaneously and independently expressed in a host cell into which the recombinant vector is introduced, thereby it is possible to overexpress the fibroblast growth factor 19 in a soluble state.