The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 14, 2023
Filed:
Apr. 08, 2019
Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Shandong, CN;
Zhejiang Zhenyuan Pharmaceutical Co., Ltd., Zhejiang, CN;
Fuli Li, Shanghai, CN;
Shian Wang, Shanghai, CN;
Weiming Fan, Shanghai, CN;
Huimin Meng, Shanghai, CN;
Kai Zhang, Shanghai, CN;
Jiaxin Li, Shanghai, CN;
ZHEJIANG ZHENYUAN BIOTECH CO. LTD., Shaoxing, CN;
QINDAO INSTITUTE OF BIOENERGY AND BIOPROCESS TECHNOLOGY, CHINESE ACADEMY OF SCIENCES, Qingdao, CN;
Abstract
The present invention discloses an engineering yeast strain for producing nervonic acids. The yeast strain over-expresses the genes related to enzymes required in a synthetic process of long-chain unsaturated fatty acids, such as fatty acid elongase, desaturase, diacylglycerol acyltransferase and the like, and optionally, further adjusts and controls the synthesis and decomposition route of triglyceride, the synthesis and decomposition route of sphingomyelin, and the synthesis and decomposition route and the oxidation-reduction balanced route of lipid subcell levels. The recombinant yeast strain can produce microorganism oil; and the content of the prepared nervonic acids accounts for 39.6% of the total fatty acids.