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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11591623 B1

PDFFull Text
Date of Patent:
Feb. 28, 2023

Filed:

Feb. 26, 2020

Dna methylation editing kit and dna methylation editing method

Applicant:

National University Corporation Gunma University, Gunma, JP;

Inventors:

Izuho Hatada, Gunma, JP;

Sumiyo Morita, Gunma, JP;

Takuro Horii, Gunma, JP;

Assignee:

NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY, Gunma, JP;

Attorney:

Wenderoth, Lind & Ponack, L.L.P.

Primary Examiner:

Celine X Qian

Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/90 (2006.01); C07K 16/18 (2006.01); C12N 5/10 (2006.01); C12N 9/10 (2006.01); C12N 15/09 (2006.01); C07K 16/44 (2006.01); C12N 1/00 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 16/18 (2013.01); C07K 16/44 (2013.01); C12N 1/00 (2013.01); C12N 5/10 (2013.01); C12N 9/10 (2013.01); C12N 15/09 (2013.01); C12N 15/111 (2013.01); C07K 2317/622 (2013.01); C07K 2319/01 (2013.01); C07K 2319/21 (2013.01); C07K 2319/60 (2013.01); C07K 2319/80 (2013.01); C12N 2310/20 (2017.05); C12Y 201/01037 (2013.01);
Abstract

A DNA methylation editing kit comprises: (1) a fusion protein of inactivated CRISPR-associated endonuclease Cas9 (dCas9) having no nuclease activity and a tag peptide array in which plural tag peptides are linked by linkers, or an RNA or DNA coding therefor; (2) a fusion protein(s) of a tag peptide-binding portion and a methylase or demethylase, or an RNA(s) or DNA(s) coding therefor; and (3) a guide RNA(s) (gRNA(s)) comprising a sequence complementary to a DNA sequence within 1 kb of a desired site of methylation or demethylation, or a DNA(s) expressing the gRNA(s).

Find Patent Forward Citations

Hatada, Izuho. (2023). Dna methylation editing kit and dna methylation editing method (U.S. Patent No. 11591623). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11591623

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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