The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2023
Filed:
Apr. 17, 2020
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventors:
Subba Reddy Palli, Lexington, KY (US);
Ramesh Kumar Dhandapani, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5146 (2013.01); A61K 9/5115 (2013.01); A61K 9/5123 (2013.01); A61K 31/713 (2013.01);
Abstract
Improved RNA interference (RNAi) efficiency in insects is disclosed herein. In particular, certain embodiments of the presently-disclosed subject matter relate to use of nanoformulations of double-stranded RNA (dsRNA) to limit nuclease degradation of the dsRNA, and enhance cellular update and intracellular transport to improve delivery of the dsRNA to enhance RNAi in insects.