The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2023
Filed:
Sep. 29, 2017
Applicant:
Baylor College of Medicine, Houston, TX (US);
Inventors:
Robert Layne Kruse, Houston, TX (US);
Karl-Dimiter Bissig, Houston, TX (US);
Stephen M. G. Gottschalk, Houston, TX (US);
Thomas C. T. Shum, Houston, TX (US);
Assignee:
BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); A61K 48/00 (2006.01); A61P 31/20 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/082 (2013.01); A61K 48/00 (2013.01); A61P 31/20 (2018.01); C07K 16/2809 (2013.01); A61K 2039/505 (2013.01); A61K 2039/53 (2013.01); C07K 2317/31 (2013.01); C07K 2317/524 (2013.01); C07K 2317/622 (2013.01); C12N 2730/10133 (2013.01); Y02A 50/30 (2018.01);
Abstract
Embodiments of the disclosure include methods and compositions for treatment of a medical condition related to the liver, including at least viral infections and liver cancer, for example. In specific embodiments, immunotherapies are provided for delivering polynucleotides locally to the liver, wherein the polynucleotides encode particular gene products that include bispecific antibodies, including those that target certain liver antigens, for example.