The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2023
Filed:
May. 01, 2018
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Lonza Walkersville Inc., Walkersville, MD (US);
Yi Zhang, Cambridge, MA (US);
Natalie Artzi, Brookline, MA (US);
Kui Wang, Quincy, MA (US);
Eytan Abraham, Potomac, MD (US);
Yonatan Levinson, Walkersville, MD (US);
Lonza Walkersville Inc., Walkersville, MD (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
Provided are methods of controlling disassociation of cells from a carrier, compositions, and methods of collecting cells. The methods of controlling disassociation of cells from a carrier may include contacting a polymeric carrier with one or more digesting agents to disassociate at least a portion of a plurality of cells from the polymeric carrier. The polymeric carrier may be crosslinked with a crosslinker including at least one of a redox sensitive moiety, a UV light sensitive moiety, a pH sensitive moiety, and a temperature sensitive moiety.