The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2023
Filed:
Apr. 23, 2020
Applicant:
Lanzatech Nz, Inc., Skokie, IL (US);
Inventors:
Shilpa Nagaraju, Skokie, IL (US);
Bakir Al-Sinawi, Sydney, AU;
Sashini De Tissera, Skokie, IL (US);
Michael Koepke, Skokie, IL (US);
Assignee:
LanzaTech NZ, Inc., Skokie, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/06 (2006.01); C12P 7/24 (2006.01); C12P 13/06 (2006.01); C12N 9/04 (2006.01); C12N 15/52 (2006.01); C12P 7/54 (2006.01); C12P 7/18 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12N 15/52 (2013.01); C12P 7/065 (2013.01); C12P 7/18 (2013.01); C12P 7/54 (2013.01); Y02E 50/10 (2013.01);
Abstract
Provided is a method of producing a product by culturing a carboxydotrophic acetogenic bacterium with a disrupting mutation in a lactate dehydrogenase enzyme in the presence of a substrate comprising CO, CO, and/or H. Preferably, the disrupting mutation reduces or eliminates the expression or activity of the enzyme such that the bacterium produces a reduced amount of lactate or no lactate.