The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2023
Filed:
Aug. 03, 2018
Amgen Inc., Thousand Oaks, CA (US);
Khaled M. K. Z. Ali, Millbrae, CA (US);
Neeraj Jagdish Agrawal, Newbury Park, CA (US);
Gunasekaran Kannan, Thousand Oaks, CA (US);
Ian Foltz, Thousand Oaks, CA (US);
Zhulun Wang, Thousand Oaks, CA (US);
Darren Bates, Thousand Oaks, CA (US);
Marissa Mock, Thousand Oaks, CA (US);
Shunsuke Takenaka, Thousand Oaks, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
Provided herein are IL-21 muteins and fusion proteins comprising the same for use in methods of treating a disease. Related conjugates, nucleic acids, vectors, host cells, pharmaceutical compositions and kits are also provided herein. Methods of making the IL-21 muteins and fusion proteins comprising the same, as well as methods of treating a subject in need thereof, are provided by the present disclosure. Further provided are PD-1 antigen-binding proteins.