The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 20, 2022
Filed:
Mar. 28, 2019
Applicant:
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Inventor:
Haitao Ji, Tampa, FL (US);
Assignee:
H. Lee Moffitt Cancer Center and Research Center Institute, Inc., Tampa, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 257/04 (2006.01); C07D 209/42 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 257/04 (2013.01); A61P 35/00 (2018.01); C07D 209/42 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01);
Abstract
Disclosed are inhibitors for the β-catenin/T-cell factor interaction. The inhibitors are selective for β-catenin/T-cell factor over β-catenin/cadherin and β-catenin/APC interactions. Methods of using the disclosed compounds to treat cancer are also disclosed.