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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11464860 B1

PDFFull Text
Date of Patent:
Oct. 11, 2022

Filed:

Oct. 25, 2018

Poly (beta-amino esters) and uses thereof

Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Daniel Griffith Anderson, Framingham, MA (US);

Kevin John Kauffman, Somerville, MA (US);

James C. Kaczmarek, Somerville, MA (US);

Asha Kumari Patel, Ilford, GB;

Assignee:

Massachusetts Institute of Technology, Cambridge, MA (US);

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

James W Rogers

Int. Cl.
CPC ...
A61K 47/18 (2017.01); A61K 9/19 (2006.01); A61K 31/7088 (2006.01); A61K 9/00 (2006.01); C12N 15/88 (2006.01); C08G 73/02 (2006.01); A61K 9/12 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01); C08G 63/685 (2006.01); A61P 11/00 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01);
U.S. Cl.
CPC ...
A61K 47/183 (2013.01); A61K 9/0019 (2013.01); A61K 9/12 (2013.01); A61K 9/19 (2013.01); A61K 31/7088 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); C08G 63/6852 (2013.01); C08G 63/6856 (2013.01); C08G 63/6858 (2013.01); C08G 73/02 (2013.01); C12N 15/88 (2013.01); A61K 31/711 (2013.01); A61K 31/7105 (2013.01); A61P 11/00 (2018.01);
Abstract

Provided herein are branched poly(beta-amino esters) (PBAE) useful as vehicles for the delivery of therapeutic agents, such as nucleic acids. The disclosed polymers form stable compositions, and are suitable for the delivery of therapeutic agents via nebulization. Compositions of the disclosed polymers are capable of delivering therapeutic agents such as mRNA to lung epithelial cells.

Find Patent Forward Citations

Anderson, Daniel. (2022). Poly (beta-amino esters) and uses thereof (U.S. Patent No. 11464860). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11464860

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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