The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Jun. 28, 2019
Grail, Llc, Menlo Park, CA (US);
Yuk-Ming Dennis Lo, Hong Kong, CN;
Rossa Wai Kwun Chiu, Hong Kong, CN;
Kwan Chee Chan, Hong Kong, CN;
Peiyong Jiang, Hong Kong, CN;
Wai Kei Lam, Hong Kong, CN;
Haiqiang Zhang, Hong Kong, CN;
GRAIL, LLC, Menlo Park, CA (US);
Abstract
Provided herein are methods and systems for identifying chimeric nucleic acid fragments, e.g., organism-pathogen chimeric nucleic acid fragments and chromosomal rearrangement chimeric nucleic acid fragments. Also provided herein are methods and systems relating to determining a pathogen integration profile or a chromosomal rearrangement in a biological sample and determining a classification of pathology based at least in part on a pathogen integration profile or a chromosomal rearrangement in a biological sample. In certain aspects of the present disclosure, cell-free nucleic acid molecules from a biological sample are analyzed.