The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Oct. 24, 2018
Applicant:

H. Lundbeck A/s, Valby, DK;

Inventors:

Gary Lesnicki, Woodinville, WA (US);

Patricia Dianne McNeill, Federal Way, WA (US);

Franz Hartner, Kundl, AT;

Mark Young, Boulder, CO (US);

Assignee:

H. LUNDBECK A/S, Valby, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2020.01); A01N 63/32 (2020.01); C07K 16/00 (2006.01); C12P 21/02 (2006.01); C12N 1/16 (2006.01); C07K 16/18 (2006.01); C07K 16/24 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 16/18 (2013.01); C07K 16/248 (2013.01); C12N 1/16 (2013.01); C12P 21/00 (2013.01); C12P 21/02 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01);
Abstract

Methods for producing heterologous proteins are disclosed. In particular, the present disclosure provides improved methods of producing desired proteins, including multi-subunit proteins such as antibodies, with a higher yield and improved purity. In exemplary embodiments, the transformed cells are a yeast, e.g., methylotrophic yeast such as


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