The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Apr. 23, 2018
Centre National DE LA Recherche Scientifique, Paris, FR;
Université DE Strasbourg, Strasbourg, FR;
Simon Fraser University, Burnaby, CA;
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Rockville, MD (US);
Michael Ryckelynck, Strasbourg, FR;
Alexis Autour, Strasbourg, FR;
Peter Unrau, North Vancouver, CA;
Elena Dolgosheina, Vancouver, CA;
Sunny Chiu Yuk Jeng, Vancouver, CA;
Shanker Shyam Sundhar Panchapakesan, North Madavilagam, IN;
Amir Abdolahzadeh, Maple Ridge, CA;
Razvan Cojocaru, Port Coquitlam, CA;
Adrian Ferré D'Amaré, Rockville, MD (US);
Robert Trachman, Rockville, MD (US);
Centre National De La Recherche, Paris, FR;
Scientifique Université De Strasbourg, Strasbourg, FR;
Simon Fraser University, Burnaby, CA;
The United States of America, As Represented by The Secretary, Department of Health and Human Services, Rockville, MD (US);
Abstract
RNA aptamers are disclosed with distinct fluorescent properties, fluorophore binding affinities, and salt dependence. Also disclosed are corresponding fluorophores, with selected fluorophores evidencing high cellular permeability. The aptamer's high fluorophore affinities, the high brightness of the bound complexes, and their thermal and salt stability, provide distinct aspects of the disclosed aptamers.