The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2022

Filed:

Nov. 06, 2018
Applicants:

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);

Depymed, Inc., Farmingdale, NY (US);

Inventors:

Nicholas Tonks, Cold Spring Harbor, NY (US);

Navasona Krishnan, Hawthorn Woods, IL (US);

Andreas Grill, Farmingdale, NY (US);

Howard Sard, Woburn, MA (US);

Assignees:

COLD SPRING HARBOR LABORATORY, Cold Spring Harbor, NY (US);

DEPYMED, INC., Farmingdale, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 31/4184 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 31/4184 (2013.01);
Abstract

Provided is a method of forming a copper-containing complex, including contacting a sample containing copper with a compound of Formula I: wherein R is —OH or —O—CH3. Also provided is a method of inhibiting enzymatic activity of a kinase in a sample, including contacting the sample with a compound of Formula I. Further provided is a method of administering to a subject a pharmaceutical composition including a compound of Formula I optionally complexed with copper. Also provided is a pharmaceutical composition including copper complexed with a compound of Formula I.


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