The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 02, 2022
Filed:
Dec. 07, 2018
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Mikhail G. Shapiro, Los Angeles, CA (US);
Jerzy O Szablowski, Valley Village, CA (US);
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61P 21/00 (2006.01); C12N 15/113 (2010.01); A61M 37/00 (2006.01); A61N 7/00 (2006.01); A61K 38/17 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 9/0019 (2013.01); A61K 38/1709 (2013.01); A61K 48/0016 (2013.01); A61K 48/0025 (2013.01); A61K 48/0066 (2013.01); A61K 48/0075 (2013.01); A61K 48/0083 (2013.01); A61M 37/00 (2013.01); A61N 7/00 (2013.01); A61P 21/00 (2018.01); C12N 15/113 (2013.01); A61N 2007/003 (2013.01); A61N 2007/0021 (2013.01); A61N 2007/0039 (2013.01);
Abstract
Provided herein are methods, systems, and related vectors and compositions allowing for noninvasive control of neural circuits. In particular, the methods and systems herein described utilize acoustically targeted chemogenetics to achieve a noninvasive neuromodulation in specifically selected cell-types among spatially selected brain regions.