The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Feb. 05, 2018
Asymchem Life Science (Tianjin) Co., Ltd, Tianjin, CN;
Hao Hong, Morrisville, NC (US);
Gage James, Morrisville, NC (US);
Jiangping Lu, Tianjin, CN;
Xingfu Xu, Tianjin, CN;
Yuxia Cui, Tianjin, CN;
Na Zhang, Tianjin, CN;
Xuewu Dong, Tianjin, CN;
Wenyan Yu, Tianjin, CN;
Xin Huang, Tianjin, CN;
Mingmin Hao, Tianjin, CN;
Yulei Ma, Tianjin, CN;
Yibing Cheng, Tianjin, CN;
Jiadong Zhao, Tianjin, CN;
ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD, Tianjin, CN;
Abstract
The invention provides a transaminase mutant and application thereof, wherein the amino acid sequence of the transaminase mutant is formed after mutation of the amino acid sequence as shown in SEQ ID NO: 1, and mutated amino acid sites comprise T7C+S47C sites. The transaminase mutant having the mutation sites can be further prepared into an immobilized enzyme through an immobilization technology, the immobilized enzyme has relatively high activity and high stability, can be recycled for multiple times, and is applicable to continuous flow reaction in a packed bed.