The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2022

Filed:

Mar. 28, 2018
Applicants:

The Johns Hopkins University, Baltimore, MD (US);

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Honggang Cui, Lutherville, MD (US);

Yi Li, Baltimore, MD (US);

Xuankuo Xu, Boxborough, MA (US);

Lye Lin Lock, Maynard, MA (US);

Zhengjian Li, Sudbury, MA (US);

Assignees:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/06 (2006.01); B01D 15/38 (2006.01); B01J 20/24 (2006.01); B01J 20/28 (2006.01); C07K 14/31 (2006.01);
U.S. Cl.
CPC ...
C07K 16/065 (2013.01); B01D 15/3809 (2013.01); B01J 20/24 (2013.01); B01J 20/28023 (2013.01); C07K 14/31 (2013.01);
Abstract

In certain embodiments, the present invention provides novel antibody purification methods and systems using a potentially simple and cost-efficient means. In some embodiments, customized Z-33 derived fromProtein A is used to construct immuno-amphiphile molecules which can assemble into immunofibers in aqueous solution with bioactive epitopes on the surface and have IgG binding ability.


Find Patent Forward Citations

Loading…