The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Apr. 02, 2020
Applicant:
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
Inventors:
Adrian Krainer, Huntington Station, NY (US);
Isabel Aznarez, Cambridge, MA (US);
Tomoki Nomakuchi, Syosset, NY (US);
Assignee:
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/713 (2006.01); C12Q 1/6883 (2018.01); A61K 31/4245 (2006.01); A61K 31/726 (2006.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); A61K 31/4245 (2013.01); A61K 31/713 (2013.01); A61K 31/726 (2013.01); C12Q 1/6883 (2013.01); C12N 2310/11 (2013.01); C12N 2320/30 (2013.01); C12N 2320/31 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract
The present disclosure relates to compositions and methods for inhibiting nonsense-mediated mRNA decay in a gene-specific manner, for example in the treatment of diseases or disorders caused by nonsense mutations.