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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11293012 B1

PDFFull Text
Date of Patent:
Apr. 05, 2022

Filed:

Jul. 08, 2016

Cells producing glycoproteins having altered n- and o-glycosylation patterns and methods and use thereof

Applicants:

Vib Vzw, Ghent, BE;

Universiteit Gent, Ghent, BE;

Inventors:

Nico Callewaert, Nevele, BE;

Leander Meuris, Ghent, BE;

Francis Santens, Ghent, BE;

Assignees:

VIB VZW, Ghent, BE;

Universiteit Gent, Ghent, BE;

Attorney:

Patent Law Works, LLP

Primary Examiner:

Richard G Hutson

Int. Cl.
CPC ...
C12N 9/24 (2006.01); C12P 21/00 (2006.01); C12N 9/90 (2006.01); C07K 14/505 (2006.01); C07K 14/535 (2006.01); C07K 14/005 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2402 (2013.01); C07K 14/005 (2013.01); C07K 14/505 (2013.01); C07K 14/535 (2013.01); C07K 14/7151 (2013.01); C12N 9/90 (2013.01); C12P 21/005 (2013.01); C12Y 204/99001 (2013.01); C12Y 302/01096 (2013.01); C12Y 501/03002 (2013.01); C07K 2319/02 (2013.01); C07K 2319/21 (2013.01); C07K 2319/30 (2013.01); C12N 2760/00051 (2013.01);
Abstract

The present application relates to the field of glyco-engineering and, more specifically, to eukaryotic cells wherein both an endoglucosaminidase is present and made deficient in UDP-galactose 4-epimerase (GalE). Typically, a glycoprotein is also present in the cells. These cells can be used to deglycosylate or partly deglycosylate the (exogenous) glycoprotein, in particular, without the need for adding an extra enzyme. Methods are also provided for the application of these cells in protein production.

Find Patent Forward Citations

Callewaert, Nico. (2022). Cells producing glycoproteins having altered n- and o-glycosylation patterns and methods and use thereof (U.S. Patent No. 11293012). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11293012

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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