The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 15, 2022

Filed:

Jan. 28, 2021
Applicant:

Emulate, Inc., Boston, MA (US);

Inventors:

Daniel Levner, Brookline, MA (US);

Christopher David Hinojosa, Cambridge, MA (US);

Norman Wen, West Roxbury, MA (US);

Antonio Varone, West Roxbury, MA (US);

Justin Nguyen, Medford, MA (US);

Lina Williamson, Chapel Hill, NC (US);

S. Jordan Kerns, Reading, MA (US);

Catherine Karalis, Brookline, MA (US);

Geraldine Hamilton, Cambridge, MA (US);

Carol Lucchesi, Westwood, MA (US);

Assignee:

EMULATE, INC, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/06 (2006.01); C12M 1/12 (2006.01); C12M 1/00 (2006.01); C12M 1/42 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); C12N 5/0793 (2010.01); C12N 5/079 (2010.01); C12N 5/071 (2010.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12M 35/04 (2013.01); C12M 23/16 (2013.01); C12M 23/38 (2013.01); C12M 25/02 (2013.01); C12M 35/08 (2013.01); C12N 5/069 (2013.01); C12N 5/0619 (2013.01); C12N 5/0622 (2013.01); C12N 5/0629 (2013.01); C12N 5/0656 (2013.01); C12N 5/0688 (2013.01); C12N 5/0697 (2013.01); C12N 5/0698 (2013.01); G01N 33/50 (2013.01); G01N 33/5082 (2013.01); G01N 33/54366 (2013.01); C12N 2501/165 (2013.01);
Abstract

A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.


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