The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 08, 2022
Filed:
Jan. 11, 2017
Applicants:
Dong Zhou, St. Louis, MO (US);
Wenhua Chu, St. Louis, MO (US);
Inventors:
Dong Zhou, St. Louis, MO (US);
Wenhua Chu, St. Louis, MO (US);
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 315/04 (2006.01); C07D 213/52 (2006.01); C07D 213/71 (2006.01); C07H 3/02 (2006.01); C07H 19/06 (2006.01); C07D 233/91 (2006.01); C07D 207/09 (2006.01); C07C 247/04 (2006.01); C07C 67/307 (2006.01); C07C 45/63 (2006.01); C07C 303/22 (2006.01); C07J 1/00 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07C 315/04 (2013.01); C07B 59/001 (2013.01); C07B 59/002 (2013.01); C07B 59/005 (2013.01); C07C 45/63 (2013.01); C07C 67/307 (2013.01); C07C 247/04 (2013.01); C07C 303/22 (2013.01); C07D 207/09 (2013.01); C07D 213/52 (2013.01); C07D 213/71 (2013.01); C07D 233/91 (2013.01); C07H 3/02 (2013.01); C07H 19/06 (2013.01); C07J 1/007 (2013.01); C07B 2200/05 (2013.01);
Abstract
The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals.