The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2022
Filed:
May. 26, 2020
National Yang Ming Chiao Tung, Taipei, TW;
Yi-Jang Lee, Taipei, TW;
Yun-Lian Lin, Taipei, TW;
Chung-Sheng Huang, Taipei, TW;
Cheng-Han Tsai, Taipei, TW;
Chun-Yuan Chang, Taipei, TW;
Bing-Ze Lin, Taipei, TW;
Yuan-Heng Tu, Taipei, TW;
Wei-Hsiang Hsu, Taipei, TW;
Pin-Ho Lo, Taipei, TW;
NATIONAL YANG-MING UNIVERSITY, Taipei, TW;
Abstract
The present invention provides an alcohol extract ofNakai ex Murata exhibits significant effects on inhibiting the senescence in human WI-38 lung fibroblasts and human dermal fibroblasts. Moreover, the alcohol extract ofis able to suppress the expression of the cofilin-1, a protein involved in actin dynamics and cell morphology and found to be increased in senescent cells. Suppression effect of cell senescence by this herb extract is more efficient in mild concentration without over-inhibition of cell viability and growth.