The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 18, 2022
Filed:
Oct. 29, 2018
Alderbio Holdings Llc, Las Vegas, NV (US);
Danielle Marie Mitchell, Seattle, WA (US);
Leon F. Garcia-Martinez, Woodinville, WA (US);
Patricia Dianne McNeill, Federal Way, WA (US);
Ethan Wayne Ojala, Snohomish, WA (US);
Mehmet Inan, Antalya, TR;
John Latham, Seattle, WA (US);
H. LUNDBECK A/S, Valby, DK;
Abstract
Methods for producing heterologous multi-subunit proteins in transformed cells are disclosed. In particular, the present disclosure provides improved methods of producing multi-subunit proteins, including antibodies and other multi-subunit proteins, which may or may not be secreted, with a higher yield and decreased production of undesired side-products. In exemplary embodiments, the transformed cells are a yeast, e.g., methylotrophic yeast such as