The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 19, 2021
Filed:
Sep. 10, 2015
Applicant:
Hsiri Therapeutics, Inc., Media, PA (US);
Inventors:
Marvin J. Miller, South Bend, IN (US);
Yun-Ming Lin, South Bend, IN (US);
Manuka Ghosh, Granger, IN (US);
Patricia A. Miller, South Bend, IN (US);
Ute Möllmann, Jena, DE;
Assignee:
HSIRI THERAPEUTICS, INC., Media, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/00 (2006.01); A61K 38/12 (2006.01); A61P 31/00 (2006.01); C07F 15/02 (2006.01); A61K 47/54 (2017.01); A61K 31/43 (2006.01); C07C 235/60 (2006.01); C07F 15/03 (2006.01); C07D 209/18 (2006.01); C07D 501/59 (2006.01); C07D 417/12 (2006.01); C07D 499/78 (2006.01); C07D 463/22 (2006.01); A61K 45/06 (2006.01); A61K 31/431 (2006.01); A61K 31/424 (2006.01); A61K 47/69 (2017.01); A61P 31/04 (2006.01); C07K 7/08 (2006.01); A61K 31/39 (2006.01); A61K 31/397 (2006.01); A61K 31/4192 (2006.01);
U.S. Cl.
CPC ...
C07F 15/025 (2013.01); A61K 31/424 (2013.01); A61K 31/43 (2013.01); A61K 31/431 (2013.01); A61K 45/06 (2013.01); A61K 47/547 (2017.08); A61K 47/6903 (2017.08); A61P 31/04 (2018.01); C07C 235/60 (2013.01); C07D 209/18 (2013.01); C07D 417/12 (2013.01); C07D 463/22 (2013.01); C07D 499/78 (2013.01); C07D 501/59 (2013.01); C07F 15/03 (2013.01); A61K 31/39 (2013.01); A61K 31/397 (2013.01); A61K 31/4192 (2013.01); A61K 38/12 (2013.01); C07K 7/08 (2013.01);
Abstract
A compound, comprising: an Fe(III)-binding and/or Fe(III)-bound siderophore; one or more optional linker covalently bound to the siderophore; and daptomycin covalently bound to the linker, or, if no linker is present, then to the siderophore; or pharmaceutically acceptable salt or solvate thereof.